LAMP 7145: Neuropathology

Course Availability:   2017-2018   2018-2019

General Information

Course Director:  Dr. H. Brent Clark

Course Coordinator: Dr. H. Brent Clark, (612) 625-7636, 


MS Year:  MS3 or MS4

Periods offered:  All periods

Total credits (weeks):  4

Consent requirement:  No

Patient care:  No

Clinical site(s):  Students will mainly be placed at:

  • FU, K-106 Deihl Hall, Fairview University Medical Center, Harvard Street at East River Road, Minneapolis, MN 55455

Students may also visit:

  • Office of the Medical Examiner, Hennepin County Medical Center, 530 Chicago Avenue, Minneapolis, MN 55415

Required session attendance:  

Typical weekly schedule:  M-F, 8:00am-5:00pm, conference schedule will be discussed and may require earlier attendance.  There are no night or weekend assignments.


Required or Elective:  Elective

Limited to student type:  No

Prerequisites:  None

Course equivalency:  None

Open to visiting students:  Yes


Discipline(s):  Lab Medicine & Pathology

Description:  The course is a practical introduction to neuropathology. The students will work with the attending neuropathologist and residents (from LMP, Neurology and/or Neurosurgery) performing diagnostic services in neuropathology. Gross autopsy brain dissections are performed at the Fairview University Medical Center and the Hennepin County Medical Examiner’s Office. In addition there are autopsy brains received in outside consultation. Neurosurgical specimens from the Fairview University Medical Center as well as consultation cases from outside hospitals also are a part of the diagnostic service. A number of teaching conferences are held in conjunction with the Departments of Neurology, Neurosurgery, Diagnostic Radiology as well as the Department of Laboratory Medicine and Pathology. A large collection of gross and microscopic specimens is available for educational uses. Ample time is allotted for independent study, and pursuit of students' individual interests in the field of neuropathology is encouraged. An understanding of neuropathology also is fundamental for anyone intending to pursue a career in any of the clinical neurosciences.
This elective allows students to experience the daily activities of a neuropathologist. The students will be become acquainted with the nature of neuropathological practice and gain insight into the role that pathologists play in patient care and validation of clinical and radiological observations. Correlation between what is seen with imaging techniques and neuropathological changes is a major emphasis of the rotation.

Course objectives:  By the end of this rotation, students will be able to:

  • identify anatomic structures within the nervous system both grossly and microscopically
  • generate a differential diagnosis for neurosurgical and autopsy specimens based on neuroimaging
  • differentiate mechanisms of neurological disease by their microscopic appearance
  • differentiate common tumors of the nervous system by their histological appearance


Graded components:

  • Regular attendance
  • Active participation in conferences, discussions and daily sign-out sessions
  • Supervisor's Assessment of competency in the approach to the gross and microscopic examination of the nervous system
  • End of rotation presentation
  • Professionalism in interactions with faculty, staff, and other members of the team

Grading scale:  H/E/S/N


An evaluation of the elective by the student will be set up in E*Value.


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